Product Name :
PUMA Rabbit pAb
Cat.No.:
db3761
Synonyms :
JFY1; PUMA; JFY-1
Application :
WB, IHC, ICC/IF, FC
Reactivity :
Human
Host species :
Rabbit
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Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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Immunogen
A synthetic peptide of human PUMA
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Gene ID
27113
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Swiss Prot
Q9BXH1
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Synonyms
JFY1; PUMA; JFY-1
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Reactivity
Human
-
Application
WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC: 1:20-1:100
ICC/IF: 1:50-1:100
FC: 1:20
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Calculated MW
21 kDa
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Observed MW
21 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.