ALIX Rabbit pAb - diagbio | 戴格生物

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ALIX Rabbit pAb

db3753

Product Name : ALIX Rabbit pAb

Cat.No.: db3753

Synonyms : AIP1; ALIX; HP95; DRIP4

Application : WB

Reactivity : Human

Host species : Rabbit

Background This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
Immunogen Recombinant protein of human ALIX
Gene ID 10015
Swiss Prot Q8WUM4
Synonyms AIP1; ALIX; HP95; DRIP4
Reactivity Human
Application WB
Recommended dilution WB: 1:1000-1:2000
Calculated MW 96 kDa
Observed MW 96 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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