CD4 Rabbit pAb - diagbio | 戴格生物

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CD4 Rabbit pAb

db3364

Product Name : CD4 Rabbit pAb

Cat.No.: db3364

Synonyms : L3T4; Ly-4

Application : WB, IHC, IP

Reactivity : Mouse

Host species : Rabbit

Background Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells.
Immunogen Recombinant protein of mouse CD4
Gene ID 12504
Swiss Prot P06332
Synonyms L3T4; Ly-4
Reactivity Mouse
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:200
IP: 1:20
Calculated MW 51 kDa
Observed MW 51 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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