Phospho-p53 (Ser392) Rabbit pAb - diagbio | 戴格生物

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Phospho-p53 (Ser392) Rabbit pAb

db33

Product Name : Phospho-p53 (Ser392) Rabbit pAb

Cat.No.: db33

Synonyms : P53; BCC7; LFS1; TRP53

Application : WB, IHC, ICC/IF, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser392 of human p53
Gene ID 7157
Swiss Prot P04637
Synonyms P53; BCC7; LFS1; TRP53
Reactivity Human
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
IP: 1:20
Calculated MW 44 kDa
Observed MW 53 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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