TMS1 Rabbit pAb - diagbio | 戴格生物

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TMS1 Rabbit pAb

db3196

Product Name : TMS1 Rabbit pAb

Cat.No.: db3196

Synonyms : ASC; TMS; TMS1; CARD5; TMS-1

Application : WB, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human TMS1
Gene ID 29108
Swiss Prot Q9ULZ3
Synonyms ASC; TMS; TMS1; CARD5; TMS-1
Reactivity Human
Application WB, FC, IP
Recommended dilution WB: 1:2000
FC: 1:20
IP: 1:20
Calculated MW 22 kDa
Observed MW 22 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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