Product Name :
DDIT3 Rabbit pAb
Cat.No.:
db3131
Synonyms :
CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; C/EBPzeta
Application :
WB, IHC
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
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Immunogen
A synthetic peptide of human DDIT3
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Gene ID
1649
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Swiss Prot
P35638
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Synonyms
CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; C/EBPzeta
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC
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Recommended dilution
WB: 1:1000-1:2000
IHC: 1:20-1:50
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Calculated MW
19 kDa
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Observed MW
27 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.