Caspase-3 Rabbit pAb - diagbio | 戴格生物

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Caspase-3 Rabbit pAb

db3108

Product Name : Caspase-3 Rabbit pAb

Cat.No.: db3108

Synonyms : CPP32; SCA-1; CPP32B

Application : WB, IHC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Immunogen Recombinant protein of human Caspase-3
Gene ID 836
Swiss Prot P42574
Synonyms CPP32; SCA-1; CPP32B
Reactivity Human, Mouse, Rat
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
IP: 1:20
Calculated MW 32 kDa
Observed MW 32,17 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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