BRG1 Rabbit pAb - diagbio | 戴格生物

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BRG1 Rabbit pAb

db3040

Product Name : BRG1 Rabbit pAb

Cat.No.: db3040

Synonyms : BRG1; CSS4; SNF2; SWI2; MRD16; RTPS2; BAF190; SNF2L4; SNF2LB; hSNF2b; BAF190A

Application : WB, IHC, ICC/IF

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Immunogen A synthetic peptide of human BRG1
Gene ID 6597
Swiss Prot P51532
Synonyms BRG1; CSS4; SNF2; SWI2; MRD16; RTPS2; BAF190; SNF2L4; SNF2LB; hSNF2b; BAF190A
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000-1:2000
IHC: 1:20-1:100
ICC/IF: 1:50
Calculated MW 185 kDa
Observed MW 220 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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