CDK4 Recombinant Rabbit mAb - diagbio | 戴格生物

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CDK4 Recombinant Rabbit mAb

db30188

Product Name : CDK4 Recombinant Rabbit mAb

Cat.No.: db30188

Synonyms : CMM3; PSK-J3

Application : IHC, WB, FC

Reactivity : Human

Host species : Rabbit

Background Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1- to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level (PMID:17253961). CCND1- CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth (PMID:21844184).
Immunogen Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1- to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level (PMID:17253961). CCND1- CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth (PMID:21844184)
Swiss Prot P11802
Synonyms CMM3; PSK-J3
Reactivity Human
Application IHC, WB, FC
Recommended dilution IHC: 1:100-1:200
Calculated MW 34 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. BP6230
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Immunohistochemistry of paraffin-embedded human dedifferentiated liposarcoma using CDK4 antibody at dilution of 1:200 (200x lens).

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