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BRG1 Recombinant Rabbit mAb
db30165
Datasheet
- Background Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex.
- Immunogen Full length protein corresponding to Human BRG1
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Swiss Prot
P51532
- Synonyms BRG1; CSS4; SNF2; SWI2; MRD16; RTPS2; BAF190; SNF2L4; SNF2LB; hSNF2b; BAF190A
- Reactivity Human
- Application IHC
- Recommended dilution IHC: 1:100-1:200
- Calculated MW 185 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6201
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human kidney using BRG1 antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 100μL 3060
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
