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p53 Recombinant Mouse mAb
db30148
Datasheet

Product Name : p53 Recombinant Mouse mAb

Cat.No.: db30148

Synonyms : P53; BCC7; LFS1; TRP53

Application : IHC

Reactivity : Human

Host species : Mouse

  • Background p53 has been observed to act as both as a tumor-suppressor and transcription factor. By binding to DNA, the normal p53 negatively regulates cell growth and division. In case of DNA damage, p53 arrests the cell cycle until repair has taken place. In case repair is not possible, p53 induces apoptosis. p53 acts a two checkpoints in the cell cycle, between G1 and S, and between G2 and M, respectively.
  • Immunogen Recombinant human wild type p53 protein was used as an immunogen
  • Swiss Prot P04637
  • Synonyms P53; BCC7; LFS1; TRP53
  • Reactivity Human
  • Application IHC
  • Recommended dilution IHC: 1:100-1:200
  • Calculated MW 58 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. BPM6168
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Immunohistochemistry of paraffin-embedded human colon cancer using p53 antibody at dilution of 1:200 (200x lens).
订购信息
  • Package Price (RMB)
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.