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ALK Recombinant Rabbit mAb
db30145
Datasheet
- Background Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase of the insulin receptor superfamily. ALK is typically expressed at low levels in regions of the developing central and peripheral nervous system. ALK may be activated in cancer through multiple mechanisms. The most common mechanism is through formation of a fusion protein from chromosomal translocations, as in the case of anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumors. ALK may also be amplified through mutation, as in neuroblastomas. Various solid tumors, such as non-small cell lung carcinoma (NSCLC) and brain cancers were also found to aberrantly express ALK.
- Immunogen Recombinant protein of Human ALK was used as an immunogen
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Gene ID
238
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Swiss Prot
Q9UM73
- Synonyms ALK1; CD246; NBLST3
- Reactivity Human
- Application IHC
- Recommended dilution IHC: 1:100-1:200
- Calculated MW 177 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6165
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human anaplastic large cell lymphoma using ALK antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 100μL 1980
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
