BackgroundNeuronal nuclei (NeuN) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, or dentate nucleus neurons. NeuN contains an RNA recognition motif and functions as a splicing regulator. NeuN regulates alternative splicing of NumB, promoting neuronal differentiation during development.
ImmunogenSynthetic peptide corresponding to residues in Human NeuN was used as an immunogen
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Immunohistochemistry of paraffin-embedded human brain using NeuN antibody at dilution of 1:200 (200x lens).