BackgroundBeta-Catenin is a key regulatory protein in Wnt signaling, a pathway that transmits signals from the cytoplasm to the nucleus, turning on the expression of specific genes in the nucleus.Under normal conditions, Beta-Catenin exists mainly in the cell membrane of normal cells, and gene mutations lead to accumulation in the nucleus.
ImmunogenSynthetic peptide corresponding to Human Beta?Catenin was used as an immunogen. The exact sequence is proprietary
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Immunohistochemistry of paraffin-embedded human breast cancer using Beta-Catenin antibody at dilution of 1:200 (200x lens).