p53 Rabbit pAb - diagbio | 戴格生物

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p53 Rabbit pAb

db2806

Datasheet

Product Name : p53 Rabbit pAb

Cat.No.: db2806

Synonyms : P53; BCC7; LFS1; TRP53

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mice deficient for this gene are developmentally normal but are susceptible to spontaneous tumors. Evidence to date shows that this gene contains one promoter, in contrast to alternative promoters of the human gene, and transcribes a few of splice variants which encode different isoforms, although the biological validity or the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human p53
Gene ID 7157
Swiss Prot P04637
Synonyms P53; BCC7; LFS1; TRP53
Reactivity Human
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000
IHC: 1:200
ICC/IF: 1:200
FC: 1:1000
IP: 1:50
Calculated MW 44 kDa
Observed MW 53 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息

Package Price (RMB)
20μL 598
50μL 998
100μL 1798
货期：现货