Product Name :
CD146 Rabbit pAb
Cat.No.:
db2710
Synonyms :
CD146; MUC18
Application :
WB, ICC/IF
Reactivity :
Human
Host species :
Rabbit
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Background
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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Immunogen
A synthetic peptide of human CD146
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Gene ID
4162
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Swiss Prot
P43121
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Synonyms
CD146; MUC18
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Reactivity
Human
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Application
WB, ICC/IF
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Recommended dilution
WB: 1:2000
ICC/IF: 1:50
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Calculated MW
72 kDa
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Observed MW
120 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.