TCF7 Rabbit pAb - diagbio | 戴格生物

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TCF7 Rabbit pAb

db2414

Product Name : TCF7 Rabbit pAb

Cat.No.: db2414

Synonyms : TCF-1

Application : WB, ICC/IF

Reactivity : Human, Mouse

Host species : Rabbit

Background This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. [provided by RefSeq, Oct 2016]
Immunogen A synthetic peptide of human TCF7
Gene ID 6932
Swiss Prot P36402
Synonyms TCF-1
Reactivity Human, Mouse
Application WB, ICC/IF
Recommended dilution WB: 1:1000
ICC/IF: 1:20
Calculated MW 42 kDa
Observed MW 28-50 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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