p57 Kip2 Rabbit pAb - diagbio | 戴格生物

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p57 Kip2 Rabbit pAb

db2389

Product Name : p57 Kip2 Rabbit pAb

Cat.No.: db2389

Synonyms : BWS; WBS; p57; BWCR; KIP2; p57Kip2

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Immunogen A synthetic peptide of human p57 Kip2
Gene ID 1028
Swiss Prot P49918
Synonyms BWS; WBS; p57; BWCR; KIP2; p57Kip2
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:50
IP: 1:20
Calculated MW 32 kDa
Observed MW 57 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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