HDAC3 Rabbit pAb - diagbio | 戴格生物

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HDAC3 Rabbit pAb

db2359

Product Name : HDAC3 Rabbit pAb

Cat.No.: db2359

Synonyms : HD3; RPD3; RPD3-2

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human HDAC3
Gene ID 8841
Swiss Prot O15379
Synonyms HD3; RPD3; RPD3-2
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC: 1:20
ICC/IF: 1:50-1:200
FC: 1:20
IP: 1:20
Calculated MW 49 kDa
Observed MW 49 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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