70 kD Neurofilament Light Rabbit pAb - diagbio | 戴格生物

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70 kD Neurofilament Light Rabbit pAb

db2351

Product Name : 70 kD Neurofilament Light Rabbit pAb

Cat.No.: db2351

Synonyms : NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110

Application : WB, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
Immunogen A synthetic peptide of human 70 kD Neurofilament Light
Gene ID 4747
Swiss Prot P07196
Synonyms NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110
Reactivity Human, Mouse, Rat
Application WB, IP
Recommended dilution WB: 1:1000-1:2000
IP: 1:20
Calculated MW 62 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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