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NLRP3 Rabbit pAb
db23100
Datasheet
- Background Enables DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including positive regulation of T-helper cell differentiation; positive regulation of cytokine production; and response to bacterium. Acts upstream of or within several processes, including NLRP3 inflammasome complex assembly; activation of cysteine-type endopeptidase activity involved in apoptotic process; and defense response to virus. Located in cytoplasm and nucleus. Part of NLRP3 inflammasome complex. Is expressed in central nervous system and retina. Used to study CINCA Syndrome; familial cold autoinflammatory syndrome 1; and non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome 1; and urticaria. Orthologous to human NLRP3 (NLR family pyrin domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
- Immunogen Recombinant protein of mouse NLRP3
-
Gene ID
216799
-
Swiss Prot
Q8R4B8
- Synonyms FCU; MWS; FCAS; Cias1; Mmig1; NALP3; Pypaf1; AII/AVP; AGTAVPRL
- Reactivity Mouse
- Application WB, ICC/IF, IP
-
Recommended dilution
WB: 1:1000
ICC/IF: 1:20
IP: 1:20 - Calculated MW 118 kDa
- Observed MW 118 kDa
- Host species Rabbit
- Clonality Polyclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 20μL 598
- 50μL 998
- 100μL 1798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
