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CDKN2A/p16INK4a Rat mAb
db22628
Datasheet
- Background Enables MDM2/MDM4 family protein binding activity; enzyme inhibitor activity; and protein N-terminus binding activity. Involved in several processes, including negative regulation of lymphocyte proliferation; positive regulation of apoptotic process; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including negative regulation of cellular protein metabolic process; negative regulation of mammary gland epithelial cell proliferation; and positive regulation of apoptotic process involved in mammary gland involution. Located in cytoplasm and granular component. Part of protein-containing complex. Is expressed in several structures, including bone marrow; central nervous system; dorsal root ganglion; eye; and testis. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); carcinoma (multiple); hematologic cancer (multiple); melanoma (multiple); and nervous system cancer (multiple). Orthologous to human CDKN2A (cyclin dependent kinase inhibitor 2A). [provided by Alliance of Genome Resources, Apr 2022]
- Immunogen Recombinant protein of mouse CDKN2A/p16INK4a
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Gene ID
12578
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Swiss Prot
P51480
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Synonyms
Arf; p16; MTS1; Pctr1; p19ARF; p16INK4a; p19
; ARF-INK4a; INK4a-ARF; Ink4a/Arf; p16(INK4a) - Reactivity Mouse
- Application IHC
- Recommended dilution IHC: 1:100
- Calculated MW 18 kDa
- Host species Rat
- Clonality Monoclonal
- Isotype IgG2a
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
