Phospho-ABCA1 (Ser2054) Rabbit pAb - diagbio | 戴格生物

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Phospho-ABCA1 (Ser2054) Rabbit pAb

db22527

Datasheet

Product Name : Phospho-ABCA1 (Ser2054) Rabbit pAb

Cat.No.: db22527

Synonyms : TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13

Application : WB, ICC/IF

Reactivity : Human, Mouse

Host species : Rabbit

Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser2054 of human ABCA1
Gene ID 19
Swiss Prot O95477
Synonyms TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13
Reactivity Human, Mouse
Application WB, ICC/IF
Recommended dilution WB: 1:2000-1:10000
ICC/IF: 1:100
Calculated MW 254 kDa
Observed MW 254 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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