HIF1 beta Rabbit pAb - diagbio | 戴格生物

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HIF1 beta Rabbit pAb

db22517

Product Name : HIF1 beta Rabbit pAb

Cat.No.: db22517

Synonyms : HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta

Application : WB, IHC, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Immunogen Recombinant protein of human HIF1 beta
Gene ID 405
Swiss Prot P27540
Synonyms HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta
Reactivity Human, Mouse, Rat
Application WB, IHC, FC
Recommended dilution WB: 1:1000
IHC: 1:50
FC: 1:50
Calculated MW 87 kDa
Observed MW 87 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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