MBD1 Rabbit pAb - diagbio | 戴格生物

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MBD1 Rabbit pAb

db21900

Product Name : MBD1 Rabbit pAb

Cat.No.: db21900

Synonyms : RFT; PCM1; CXXC3

Application : WB, IHC, ICC/IF

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
Immunogen A synthetic peptide of human MBD1
Gene ID 4152
Swiss Prot Q9UIS9
Synonyms RFT; PCM1; CXXC3
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
Calculated MW 67 kDa
Observed MW 67 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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