TrkA Rabbit pAb - diagbio | 戴格生物

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TrkA Rabbit pAb

db21537

Product Name : TrkA Rabbit pAb

Cat.No.: db21537

Synonyms : MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA

Application : WB, IHC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human TrkA
Gene ID 4914
Swiss Prot P04629
Synonyms MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:50
Calculated MW 88 kDa
Observed MW 140 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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