Caspase-11 Rabbit pAb - diagbio | 戴格生物

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Caspase-11 Rabbit pAb

db2124

Product Name : Caspase-11 Rabbit pAb

Cat.No.: db2124

Synonyms : Caspl; ich-3; CASP-4; Casp11; CASP-11

Application : WB, IP

Reactivity : Mouse

Host species : Rabbit

Background This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]
Immunogen Recombinant protein of mouse Caspase-11
Gene ID 12363
Swiss Prot P70343
Synonyms Caspl; ich-3; CASP-4; Casp11; CASP-11
Reactivity Mouse
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 43 kDa
Observed MW 43,38,25 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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