Phospho-JNK1/JNK2/JNK3 (Tyr185/Tyr185/Tyr223) Rabbit pAb
Product Name :
Phospho-JNK1/JNK2/JNK3 (Tyr185/Tyr185/Tyr223) Rabbit pAb
Cat.No.:
db20565
Synonyms :
JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
Application :
WB, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
-
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
-
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr185/Tyr185/Tyr223 of human JNK1+JNK2+JNK3
-
Gene ID
5599
-
Swiss Prot
P45983
-
Synonyms
JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
-
Reactivity
Human, Mouse, Rat
-
Application
WB, IP
-
Recommended dilution
WB: 1:5000
IP: 1:20
-
Calculated MW
48 kDa
-
Observed MW
46,54 kDa
-
Host species
Rabbit
-
Clonality
Polyclonal
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
20μL
698
-
50μL
1398
-
100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号