Insulin Rabbit pAb - diagbio | 戴格生物

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Insulin Rabbit pAb

db20504

Product Name : Insulin Rabbit pAb

Cat.No.: db20504

Synonyms : IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10

Application : IHC

Reactivity : Human

Host species : Rabbit

Background This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020]
Immunogen A synthetic peptide of human Insulin
Gene ID 3630
Swiss Prot P01308
Synonyms IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10
Reactivity Human
Application IHC
Recommended dilution IHC: 1:50
Calculated MW 12 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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