Activin Receptor Type IIB Rabbit pAb - diagbio | 戴格生物

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Activin Receptor Type IIB Rabbit pAb

db20325

Datasheet

Product Name : Activin Receptor Type IIB Rabbit pAb

Cat.No.: db20325

Synonyms : HTX4; ACTRIIB; ActR-IIB

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Activin Receptor Type IIB/ACVR2B
Gene ID 93
Swiss Prot Q13705
Synonyms HTX4; ACTRIIB; ActR-IIB
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 58 kDa
Observed MW 58 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息

Package Price (RMB)
20μL 598
50μL 998
100μL 1798
货期：现货