alpha Actinin Rabbit pAb - diagbio | 戴格生物

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alpha Actinin Rabbit pAb

db1866

Product Name : alpha Actinin Rabbit pAb

Cat.No.: db1866

Synonyms : BDPLT15

Application : WB, IHC, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human alpha Actinin
Gene ID 87
Swiss Prot P12814
Synonyms BDPLT15
Reactivity Human, Mouse, Rat
Application WB, IHC, FC, IP
Recommended dilution WB: 1:2000
IHC: 1:20
FC: 1:20
IP: 1:20
Calculated MW 103 kDa
Observed MW 103 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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