Product Name :
Notch1 Rabbit pAb
Cat.No.:
db1840
Synonyms :
hN1; AOS5; TAN1; AOVD1
Application :
WB, IHC, ICC/IF, FC
Reactivity :
Human, Mouse
Host species :
Rabbit
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Background
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]
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Immunogen
A synthetic peptide of human Notch1
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Gene ID
4851
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Swiss Prot
P46531
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Synonyms
hN1; AOS5; TAN1; AOVD1
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Reactivity
Human, Mouse
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Application
WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
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Calculated MW
273 kDa
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Observed MW
120 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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