Mre11 Rabbit pAb - diagbio | 戴格生物

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Mre11 Rabbit pAb

db163

Product Name : Mre11 Rabbit pAb

Cat.No.: db163

Synonyms : ATLD; HNGS1; MRE11A; MRE11B

Application : WB, IHC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Mre11
Gene ID 4361
Swiss Prot P49959
Synonyms ATLD; HNGS1; MRE11A; MRE11B
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:1000-1:5000
IHC: 1:20-1:50
Calculated MW 81 kDa
Observed MW 81 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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