CD4 Recombinant Rabbit mAb - diagbio | 戴格生物

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CD4 Recombinant Rabbit mAb

db16127

Product Name : CD4 Recombinant Rabbit mAb

Cat.No.: db16127

Synonyms : T4; IMD79; Leu-3; OKT4D; CD4mut

Application : IHC, FC

Reactivity : Human

Host species : Rabbit

Background This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
Immunogen A synthetic peptide of human CD4
Gene ID 920
Swiss Prot P01730
Synonyms T4; IMD79; Leu-3; OKT4D; CD4mut
Reactivity Human
Application IHC, FC
Recommended dilution IHC: 1:200
FC: 1:100
Calculated MW 51 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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