Bcl-XL Recombinant Rabbit mAb - diagbio | 戴格生物

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Bcl-XL Recombinant Rabbit mAb

db16019

Product Name : Bcl-XL Recombinant Rabbit mAb

Cat.No.: db16019

Synonyms : BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
Immunogen A synthetic peptide of human Bcl-XL
Gene ID 598
Swiss Prot Q07817
Synonyms BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:200
ICC/IF: 1:100
FC: 1:20
IP: 1:30
Calculated MW 26 kDa
Observed MW 30 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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