TAB1 Recombinant Rabbit mAb - diagbio | 戴格生物

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TAB1 Recombinant Rabbit mAb

db15922

Datasheet

Product Name : TAB1 Recombinant Rabbit mAb

Cat.No.: db15922

Synonyms : 3'-Tab1; MAP3K7IP1

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human TAB1
Gene ID 10454
Swiss Prot Q15750
Synonyms 3'-Tab1; MAP3K7IP1
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:20-1:100
ICC/IF: 1:20-1:50
FC: 1:20-1:100
IP: 1:20
Calculated MW 55 kDa
Observed MW 55 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息

Package Price (RMB)
20μL 698
50μL 1398
100μL 2398
货期：现货