CD11b Recombinant Rabbit mAb - diagbio | 戴格生物

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CD11b Recombinant Rabbit mAb

db15861

Product Name : CD11b Recombinant Rabbit mAb

Cat.No.: db15861

Synonyms : CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6

Application : WB, IHC

Reactivity : Human, Mouse

Host species : Rabbit

Background This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Immunogen A synthetic peptide of human CD11b
Gene ID 3684
Swiss Prot P11215
Synonyms CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6
Reactivity Human, Mouse
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:50
Calculated MW 127 kDa
Observed MW 170 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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