SQSTM1/p62 Recombinant Rabbit mAb - diagbio | 戴格生物

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SQSTM1/p62 Recombinant Rabbit mAb

db15523

Product Name : SQSTM1/p62 Recombinant Rabbit mAb

Cat.No.: db15523

Synonyms : p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Immunogen A synthetic peptide of human SQSTM1/p62
Gene ID 8878
18412
113894
Swiss Prot Q13501
Q64337
O08623
Synonyms p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:5000-1:50000
IHC: 1:200-1:500
ICC/IF: 1:200-1:500
FC: 1:20
Calculated MW 48 kDa
Observed MW 62 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from HCT116, T24 cells using db15523 at 1:10000.

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