GSDMD Recombinant Rabbit mAb
Product Name :
GSDMD Recombinant Rabbit mAb
Cat.No.:
db15296
Synonyms :
DF5L; M2-4; Dfna5l; Gsdmdc1; AW558049; 1810036L03Rik
Application :
WB, IP
Reactivity :
Mouse
Host species :
Rabbit
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Background
Gasdermin-D, N-terminal: Promotes pyroptosis in response to microbial infection and danger signals. Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4 in response to canonical, as well as non-canonical (such as cytosolic LPS) inflammasome activators (PubMed:26611636, PubMed:26375259, PubMed:26375003, PubMed:27418190, PubMed:27385778, PubMed:27383986). After cleavage, moves to the plasma membrane where it strongly binds to membrane inner leaflet lipids, including monophosphorylated phosphatidylinositols, such as phosphatidylinositol 4-phosphate, bisphosphorylated phosphatidylinositols, such as phosphatidylinositol (4,5)-bisphosphate, as well as phosphatidylinositol (3,4,5)-trisphosphate, and more weakly to phosphatidic acid and phosphatidylserine.
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Immunogen
A synthetic peptide of mouse GSDMD
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Gene ID
69146
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Swiss Prot
Q9D8T2
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Synonyms
DF5L; M2-4; Dfna5l; Gsdmdc1; AW558049; 1810036L03Rik
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Reactivity
Mouse
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Application
WB, IP
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Recommended dilution
WB: 1:1000
IP: 1:20-1:50
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Calculated MW
53 kDa
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Observed MW
53 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.