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CD4 (DGR14475) Rabbit mAb
db15291
Datasheet
- Background Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells.
- Immunogen Recombinant protein of mouse CD4
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Gene ID
12504
-
Swiss Prot
P06332
- Synonyms L3T4; Ly-4
- Reactivity Mouse
- Application WB, IHC-P, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:1000
IP: 1:20-1:50 - Calculated MW 51 kDa
- Observed MW 51 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR14475
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Mouse thymus tissue using db15291 at 1:1000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
