Apolipoprotein E (DGR14977) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Apolipoprotein E (DGR14977) Rabbit mAb

db15177

Datasheet

Product Name : Apolipoprotein E (DGR14977) Rabbit mAb

Cat.No.: db15177

Synonyms : AD2; LPG; APO-E; ApoE4; LDLCQ5

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
Immunogen A synthetic peptide of mouse Apolipoprotein E
Gene ID 348
Swiss Prot P08226
Synonyms AD2; LPG; APO-E; ApoE4; LDLCQ5
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC-P: 1:500-1:5000
ICC/IF: 1:200-1:500
FC: 1:50-1:100
IP: 1:20-1:50
Calculated MW 36 kDa
Observed MW 36 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR14977
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from HepG2 cells and Rat brain tissue using db15177 at 1:1000.
Western blot analysis of extracts from Mouse liver tissue using db15177 at 1:1000.

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