5HT2C Receptor Recombinant Rabbit mAb - diagbio | 戴格生物

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5HT2C Receptor Recombinant Rabbit mAb

db15044

Datasheet

Product Name : 5HT2C Receptor Recombinant Rabbit mAb

Cat.No.: db15044

Synonyms : HTR1C; 5-HT1C; 5-HT2C; 5HTR2C; 5-HTR2C

Application : WB

Reactivity : Human

Host species : Rabbit

Background This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]
Immunogen A synthetic peptide of human 5HT2C Receptor
Gene ID 3358
Swiss Prot P28335
Synonyms HTR1C; 5-HT1C; 5-HT2C; 5HTR2C; 5-HTR2C
Reactivity Human
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 52 kDa
Observed MW 52 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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