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p57 Kip2 (DGR34243) Rabbit mAb
db14920
Datasheet
- Background This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
- Immunogen A synthetic peptide of human p57 Kip2
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Gene ID
1028
-
Swiss Prot
P49918
- Synonyms BWS; WBS; p57; BWCR; KIP2; p57Kip2
- Reactivity Human
- Application WB, IHC-P, IP
-
Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:100-1:200
IP: 1:10-1:100 - Calculated MW 32 kDa
- Observed MW 57 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR34243
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HCT116,SCC-9 cells using db14920 at 1:1000. -
Immunohistochemical analysis of paraffin-embedded human breast cancer using db14920 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
