Phospho-MEK4 (Ser80) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-MEK4 (Ser80) Recombinant Rabbit mAb

db14900

Product Name : Phospho-MEK4 (Ser80) Recombinant Rabbit mAb

Cat.No.: db14900

Synonyms : JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1

Application : WB, IHC, IP

Reactivity : Human, Mouse

Host species : Rabbit

Background This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser80 of human MEK4/MKK4
Gene ID 6416
Swiss Prot P45985
Synonyms JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1
Reactivity Human, Mouse
Application WB, IHC, IP
Recommended dilution WB: 1:2000
IHC: 1:20
IP: 1:20
Calculated MW 44 kDa
Observed MW 44 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of MEK4/MKK4 (phospho-Ser80) in A549,MCF-7,U251 cell lysates using MEK4/MKK4 (phospho-Ser80) antibody(1:1000 diluted).

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