Caspase-3 (DGR20964) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Caspase-3 (DGR20964) Rabbit mAb

db14868

Datasheet

Product Name : Caspase-3 (DGR20964) Rabbit mAb

Cat.No.: db14868

Synonyms : CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Caspase-3; A830040C14Rik

Application : WB

Reactivity : Mouse

Host species : Rabbit

Background This gene encodes a protein that belongs to a highly conserved family of cysteinyl aspartate-specific proteases that function as essential regulators of programmed cell death through apoptosis. Members of this family contain an N-terminal pro-domain and require cleavage at specific aspartate residues to become mature. The protein encoded by this gene belongs to a subgroup of cysteinyl aspartate-specific proteases that are activated by initiator caspases and that perform the proteolytic cleavage of apoptotic target proteins. Mice defective for this gene exhibit a variety of phenotypes including reduced neuronal apoptosis resulting in hyperplasias, hearing loss, attenuated osteogenic differentiation of bone marrow stromal stem cells, and pre- and post-natal lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Immunogen A synthetic peptide of mouseCleaved Caspase-3
Gene ID 12367
Swiss Prot P70677
Synonyms CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Caspase-3; A830040C14Rik
Reactivity Mouse
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 32 kDa
Observed MW 32,17 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20964
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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