68kDa Neurofilament Recombinant Rabbit mAb
Product Name :
68kDa Neurofilament Recombinant Rabbit mAb
Cat.No.:
db14746
Synonyms :
NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110
Application :
WB, IHC, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
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Immunogen
Recombinant protein of mouse 68kDa Neurofilament
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Gene ID
4747
18039
83613
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Swiss Prot
P08551
P08551
P19527
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Synonyms
NFL; NF-L; NF68; CMT1F; CMT2E; PPP1R110
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC, IP
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Recommended dilution
WB: 1:1000
IHC: 1:200
IP: 1:20
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Calculated MW
62 kDa
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Observed MW
68 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from Mouse brain tissue using db14746 at 1:1000.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.