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Caspase-11 (DGR13235) Rabbit mAb
db14701
Datasheet
- Background This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]
- Immunogen Recombinant protein of mouse Caspase-11
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Gene ID
12363
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Swiss Prot
P70343
- Synonyms Caspl; ich-3; CASP-4; Casp11; CASP-11
- Reactivity Mouse
- Application WB, IP
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Recommended dilution
WB: 1:1000
IP: 1:50 - Calculated MW 43 kDa
- Observed MW 43,38,25 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13235
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Caspase-11 in C6,3T3,Hela cell lysates using Caspase-11 antibody(1:1000 diluted). -
Western blot analysis of extracts from SW620 cells and Mouse liver tissue using db14701 at 1:1000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
