XPD Recombinant Rabbit mAb - diagbio | 戴格生物

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XPD Recombinant Rabbit mAb

db14606

Product Name : XPD Recombinant Rabbit mAb

Cat.No.: db14606

Synonyms : EM9; TTD; XPD; TTD1; COFS2; TFIIH

Application : WB, IHC, ICC/IF

Reactivity : Human

Host species : Rabbit

Background The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Immunogen A synthetic peptide of human XPD
Gene ID 2068
Swiss Prot P18074
Synonyms EM9; TTD; XPD; TTD1; COFS2; TFIIH
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000-1:5000
IHC: 1:50
ICC/IF: 1:100
Calculated MW 87 kDa
Observed MW 80 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of XPD in Jurkat,Hela cell lysates using XPD antibody(1:500 diluted).

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