AMPK gamma 1 Recombinant Rabbit mAb
Product Name :
AMPK gamma 1 Recombinant Rabbit mAb
Cat.No.:
db14570
Synonyms :
AMPKG
Application :
WB, FC, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human AMPK gamma 1
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Gene ID
5571
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Swiss Prot
P54619
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Synonyms
AMPKG
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Reactivity
Human, Mouse, Rat
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Application
WB, FC, IP
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Recommended dilution
WB: 1:1000
FC: 1:20
IP: 1:20
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Calculated MW
38 kDa
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Observed MW
38 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of AMPK gamma 1 in CHO-K1,C6,Jurkat cell lysates using AMPK gamma 1 antibody(1:500 diluted).
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Western blot analysis of extracts from Rat heart,Mouse brain tissue using db14570 at 1:1000.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.