BackgroundThis gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
ImmunogenRecombinant protein of human Collagen III
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of Collagen III in K562,C6,3T3 cell lysates using Collagen III antibody(1:1000 diluted).
Western blot analysis of extracts from A549 293T cells using db14567 at 1:1000.
Immunofluorescent analysis of HeLa cells using db14567 antibody (green), and DAPI (blue).